A Robust Portfolio of Cancer Clinical Trials

Adult Clinical Trials
View all active adult clinical trials available through the Froedtert & the Medical College of Wisconsin Cancer Network.

Pediatric Clinical Trials
Find a list of clinical trials available through Children’s Wisconsin as well as questions for your care team.

Physician Referrals
Visit MCW Physician ACCESS (All Cancer Center Enrolling Studies) to locate a potential match for adult and pediatric patients.
A Leader in Cancer Clinical Trials
The MCW Cancer Center is recognized by the National Cancer Institute as a Lead Academic Participating Site for its scientific leadership, the strength and innovation of its research and science, and robust participation in National Clinical Trials Network clinical trials. The Center is one of only 32 institutions in the United States to achieve this designation, and the only institution in Milwaukee and the eastern Wisconsin region.


Translational Research Units
The Froedtert & MCW Cancer Network is one of a few cancer care networks in the nation with two dedicated cancer translational research units and has the only cancer inpatient translational research unit in Wisconsin. These translational research units focus on early-phase clinical trials that are conducted among a small numbers of patients. Early-phase clinical trials are essential to evaluating promising new therapies that may lead to FDA approval as standard treatment of care.
The Importance of Clinical Trials
Eradicating cancer means investigating how cancer impacts everyone – and discovering treatments for all types of patients. MCW Cancer Center investigators (the physicians and researchers producing clinical trials) collect more reliable data when more people participate in a clinical trial. The more patients who qualify, the greater the chances the study will reflect the outcomes of the real-world population that will eventually use the new therapy.
If you’re eligible for a clinical trial and decide that’s the next best step for you, we’ll work to ensure you have the support needed to participate.


Groundbreaking #HOPE4LIVER Trial Uses Sound Waves to Save Lives
A nationwide #HOPE4LIVER trial remains underway to evaluate an innovative, patient-centered treatment for liver tumors. Using a combination of robotics and histotripsy (a technique that uses sound waves to liquefy and destroy cancer tissue), this non-invasive treatment holds the potential for quicker patient recovery.

Innovative Treatment "Tricks" and Destroys Cancer Cells
A new trial is underway to study a non-invasive treatment with the potential to slow growth and reduce the size of glioblastoma, an aggressive form of brain cancer.

Inclusion is Key to Unlocking New Therapies
MCW Cancer Center investigators are spearheading first-of-its-kind research to identify life-saving treatments for Acute Myeloid Leukemia in children with Down Syndrome. As cancer treatments become more and more individualized, the team’s findings highlight the importance of inclusion in clinical trials.

CAR-T Therapy Slows Multiple Myeloma in Patients Who Have Stopped Responding to Other Treatments
In a Phase 3 study, MCW Cancer Center investigators found that patients with Multiple Myeloma who were treated with a unique CAR-T therapy experienced significantly positive results, findings which could lead to a new standard of care for the treatment of this disease.

Clinical Trial Identifies New Therapy for Graft Versus Host Disease
MCW Cancer Center scientists identify new therapy to reduce the severity of gastrointestinal graft versus host disease and improve patient outcomes.

Drug Therapy Offers New Hope for Patients with Mantle Cell Lymphoma
Groundbreaking results from a recent clinical trial found that Pirtobrutinib significantly improved life expectancy for patients with mantle cell lymphoma who responded poorly to other treatments. These results led to accelerated approval of Pirtobrutinib by the Food and Drug Administration.