Research Programs

The Medical College of Wisconsin Cancer Center’s three high-impact cancer research programs are led by scientists whose research interests are interrelated and focused on uncovering new approaches for the diagnosis, prevention, and treatment of cancer.
Three researchers using an interactive geospatial cancer map on a large screen display

Cancer Control

This program studies how behavioral, clinical, environmental, and social factors influence cancer risk, treatment, and survivorship. Researchers use clinical data and population-based approaches to identify gaps in care, define drivers of disparities, and develop interventions that improve screening, access, and outcomes across the cancer continuum.
Researcher in lab coat and gloves conducting laboratory experiment

Cancer Biology

This program investigates how tumors arise, evolve, and resist therapy by defining the biological mechanisms that drive cancer at the molecular, cellular, and system levels. Investigators identify disease dependencies, map vulnerabilities in cancer cells, and uncover targets and pathways that can be advanced toward new therapeutic strategies.

Researcher in lab coat and gloves conducting an experiment

Discovery and Developmental Therapeutics

This program advances new cancer therapies from discovery through preclinical development and early-phase clinical testing. Investigators identify and validate therapeutic targets, develop novel agents and combinations, and translate promising findings into investigator-initiated and first-in-human clinical trials.

Integrated Disease-Oriented Teams

Research programs are further enhanced by 16 integrated Disease-Oriented Teams (iDOTs) comprised of basic, translational, clinical, and population health scientists focused on specific disease areas. Through multi-disciplinary collaboration, these teams hold the shared goal of translating discoveries into new treatments and therapies.

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Deepak Kilari, MD

Chair, Adult Early Phase

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Nirav Shah, MD

Chair, BMT/Cell Therapy

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Lubna Chaudhary, MD

Chair, Breast

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Jennifer Connelly, MD

Chair, Central Nervous System

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Alexandria Phan, MD, FACP

Chair, Gastrointestinal

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Peter Langenstroer, MD, MS

Chair, Genitourinary

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Denise Uyar, MD

Chair, Gynecology

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Stuart Wong, MD

Chair, Head and Neck

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Guru Subramanian Guru Murthy, MD, MS

Chair, Leukemia

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Sumana Devata, MD

Chair, Lymphoma

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Michael James Burke, MD

Chair, Pediatrics

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Anita D'Souza, MD

Chair, Plasma Cell Disorders

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Kelly Rentscher, PhD

Chair, Population Sciences and Behavioral Health

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John Charlson, MD

Chair, Sarcoma

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Callisia Clarke, MD, MS, FACS, FSSO

Chair, Skin

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Lindsay Puckett, MD

Chair, Thoracic