Translational Metabolomics Shared Resource (TraMSR)

The Translational Metabolomics Shared Resource supports cancer metabolism research, spanning from the analysis of molecules to organelles, to cells and tissues.

Scheduling, Location, and Hours of Operation

Mass Spectrometry: Translational and Biomedical Research Center, 2nd floor
Redox and Bioenergetics: MACC Fund Research Center, 2nd floor
Preclinical and Clinical Imaging: Medical Imaging Research Center, 1st floor
Monday–Friday from 8 a.m.-5 p.m.
Submit a TraMSR iLab request


TraMSR provides a broad range of analytical tools for lipidomic, metabolomic, glycomic, and proteomic characterization of preclinical and patient samples.
Mass Spectrometry
  • Sample Preparation
  • Metabolomics
  • Lipidomics
  • Glycomics
  • Glycoproteomics
  • MALDI Imaging
  • Data analysis
Redox and Bioenergetics
  • ROS measurements and probes
  • GSH/GSSG measurements
  • Redox immunoblotting
  • Metabolic pathway profiling
  • Mitochondrial oxygen consumption
  • Glycolytic function
  • Mitochondrial membrane potential
  • Metabolic reprogramming
Preclinical and Clinical Imaging
  • Bioluminescence and florescence
  • Small animal CT imaging
  • Small animal NIR and Short-Wave Infrared Imaging (SWIR)
  • Patient tumor and lymph node measurements
  • Patient longitudinal calculation [?]
  • Clinical trial level reporting
  • Audit support
  • Clinical radio-pathomics
  • Clinical PET-MRI (future)
Clinical Trial Response Assessment
  • Tumor and lymph node measurements
  • Longitudinal calculation
  • Trial level reporting
  • Audit support


TraMSR provides state-of-the-art instrumentation and software enabling mass spectrometry analyses of the tumor metabolome, including identification and visualization of sugars, lipids, proteins and nucleic acids; mitochondrial bioenergetic and redox functional analyses; preclinical imaging of tumors and the microenvironment; and clinical biomarker imaging and assessments of tumor growth in clinical trial patients.
Mass Spectrometry
  • Bruker timsTOF Flex MALDI imaging
  • Thermo Ascend and Fusion Lumos
Redox and Bioenergetics
  • Seahorse extracellular flux analyzers
  • HPLC and UHPLC systems
  • Plate readers
  • Electron paramagnetic resonance (EPR) and luminescence spectrometers
Preclinical and Clinical Imaging
  • IVIS-100 and IVIS Spectrum-CT
  • NIR in-vivo imaging
  • Cloud based image repository and tools for trial assessments
  • Human PET-MRI (future)



Peter LaViolette, PhD

Director, Translational Metabolomics Shared Resource (TraMSR)